Dr. Katia Sayyed

Postdoctoral Research Fellow
School of Arts and Sciences - Natural Sciences Department

Dr. Katia Sayyed joined LAU-School of Arts and Sciences (SoAS) as a postdoctoral research fellow working on projects in the field of Environmental Toxicology (2019-2021), under the supervision of Dr. Christian Khalil. During this period, her work yielded two publications investigating the toxic effect of petroleum volatile organic compound emissions in A549 cell line in vitro (Sayyed et al. 2022)and in mice in vivo (Nour‐Eldine et al. 2022). She also teaches several courses at LAU including BIO 222 and BIO489. Recently, she is a research faculty working on strategic plans within the Graduate Studies and Research office (GSR) at LAU. She holds a BS in “Biochemistry” and Masters in “Applied Biotechnology” from the Lebanese University, where her main research activities were focused on cigarette smoke and chlorpromazine toxicity in the yeast model Saccharomyces cerevisiae (Sayyed et al. 2019). She was awarded AZM-scholarship to pursue her PhD degree in “Toxicology and Biotechnology”, in joint supervision between the Lebanese University and Rennes-1 University (France). During her PhD, she studied the interactions of cigarette smoke condensate and its contained chemicals with drug transporters in hepatic and non-hepatic cell models (Sayyed et al. 2017; Sayyed et al. 2016; Sayyed et al. 2018). Her research interests are related to the toxicological impact of contaminants and environmental pollutants in humans in all its aspects, including contaminant-drug transporter interactions, environmental pollutants cytotoxicity and genotoxicity.

Publications

Nour‐Eldine, W., Sayyed, K., Harhous, Z., Dagher‐Hamalian, C., Mehanna, S., Achkouti, D., ElKazzaz, H., Khnayzer, R.S., Kobeissy, F. and Khalil, C. 2022. Gasoline fume inhalation induces apoptosis, inflammation, and favors Th2 polarization in C57BL/6 mice. Journal of Applied Toxicology.

Sayyed, K., Aljebeai, A.-K., Al-Nachar, M., Chamieh, H., Taha, S. and Abdel-Razzak, Z. 2019. Interaction of cigarette smoke condensate and some of its components with chlorpromazine toxicity on Saccharomyces cerevisiae. Drug and chemical toxicology, 1-11.

Sayyed, K., Le Vee, M., Abdel-Razzak, Z. and Fardel, O. 2017. Inhibition of organic anion transporter (OAT) activity by cigarette smoke condensate. Toxicology in Vitro 44, 27-35.

Sayyed, K., Le Vee, M., Abdel-Razzak, Z., Jouan, E., Stieger, B., Denizot, C., Parmentier, Y. and Fardel, O. 2016. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology 363, 58-71.

Sayyed, K., Le Vée, M., Chamieh, H., Fardel, O. and Abdel-Razzak, Z. 2018. Cigarette smoke condensate alters Saccharomyces cerevisiae efflux transporter mRNA and activity and increases caffeine toxicity. Toxicology 409, 129-136.

Sayyed, K., Nour-ElDine, W., Rufka, A., Mehanna, S., Khnayzer, R.S., Abi-Gerges, A. and Khalil, C. 2022. Acute cytotoxicity, genotoxicity, and apoptosis induced by petroleum VOC emissions in A549 cell line. Toxicology in Vitro, 105409.